Assessment of Immediate Adverse Reactions After the Initial Administration of COVID-19 Vaccines in Residents of Australia

Assessment of Immediate Adverse Reactions After the Initial Administration of COVID-19 Vaccines in Residents of Australia

*Farhan Saleem
Edith Cowan University, Perth, Western Australia

Reehana Khawaja
Sarah Medical Center, Chicago Illinois, USA

*Corresponding address: Edith Cowan University, Perth, Western Australia
Email: dr.farhansaleem13@gmail.com

doi:
Keywords: Community; Data; Health; Patient; Public; Vaccines

 

ABSTRACT

Objective

Our objective was to explore the extent and severity of reported injurious effects, with a focus on variations linked to the type of vaccine administered.

Methods

A survey involving 1435 COVID-19 vaccine adult recipients was conducted via online social media websites and emails from April to November 2022. Potential associations between reported side effects and factors such as gender, age, comorbidities, and prior or recurrent COVID-19 infection was examined, stratified by vaccine type.

Results

Primary side effects reported by study participants included pain at the injection site (47.2%), drowsiness and fatigue (22.8%), headache (18%), and muscle / joint pain (11.5%). Notably, recipients of the P vaccine exhibited a much higher prevalence of adverse effects in comparison to those receiving the inactivated S vaccine (odds ratio of 1.28 (95% CI 1.23–1.57). The number of side effects reported per person for P and S vaccines was 2.48 ± 2.27 and 1.72 ± 1.79 respectively, demonstrating a statistically significant difference between the two (p < 0.001). Instances of severe side effects post-COVID-19 vaccination were infrequent, with 93% of reported symptoms categorized as mild and requiring none or home-based care.

Conclusion

This research identified certain demographic and vaccine-related factors associated with a higher likelihood of adverse effects post-COVID-19 vaccination. Specifically, individuals aged below 55, females, those with one or more comorbid diseases, recipients of the P vaccine, and those with a history of COVID-19 infection were found to have elevated odds of developing adverse effects compared to their counterparts.

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How to Cite this: Saleem F, Khawaja R. Assessment of Immediate Adverse Reactions After the Initial Administration of COVID 19 Vaccines in Residents of Australia. J Sci Technol Educ Art Med. 2024;1(1):1-6

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